PX-41 also seems to enhance the digestive system significantly, as subjects are able to consume and dissolve massive objects inside their stomach almost instantly. Subjects enhanced by this chemical are heavily resistant against attacks such as explosives, blunt force trauma, bullets, and heat - both internally and externally. It stimulates various growths, most notably physical toughness. PX-41 mutates its host into a purple monstrosity, changing their colors as well as skin. This mutagen can be activated by drinking or injection. The PX-41 is no longer seen after the events of the film. He is subsequently knocked out with Nefario's Fart Gun and presumably incarcerated by AVL. After multiple attempts, Gru disables him with the lipstick taser. Nefario also leaves El Macho's employ and develops the PX-41 antidote, which Gru would use later to restore the converted minions back to normal.Įl Macho, seeing his army decimated, takes the PX-41 serum and transforms into a monstrosity. El Macho demands an alliance with Gru due to the mutagen's potential, although Gru turns it down and leaves, unwilling to co-operate due to his retirement. Nefario (who has left Gru earlier for more lucrative opportunities) and is displayed the results of the mutagen. Gru later enters El Macho's lair and finds him with Dr. Gru and Lucy infiltrated Salsa & Salsa in hopes of retrieving a sample, but it turned out to be simply Salsa. This prompts the AVL to employ Felonius Gru, who is tasked with arresting the culprit and finding the mutagen. PX-41 is stolen by El Macho at the start of Despicable Me 2.
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